One bit-flipping NIC took down Amazon's cloud storage (2008)

Official statement:
Amazon S3 Availability Event: July 20, 2008

Peter Vosshall in the video below says

… it took down s3 completely. So one server, one NIC, one bit, took down our regional service and that was the only layer - we had checksumming all the way up and down the stack - that was the only layer that didn’t have the checksumming.

As seen on HN:

Reminds me of a rogue NIC, flipping a single bit every now and then, that took down S3: